St. Lawrence is thought to have been born on 31 December AD 225, in Huesca (or less probably, in Valencia), the town from which his parents came in the later region of Aragon that was then part of the Roman province of Hispania Tarraconensis. The martyrs Orentius and Patientia are traditionally held to have been his parents.
Lawrence encountered the future Pope Sixtus II, a famous teacher born in Greece, in Caesaraugusta (Zaragoza), and they travelled together from Spain to Rome. When Sixtus became the Pope in 257, he ordained the young Lawrence who was only 22, as a deacon, and later appointed him as "archdeacon of Rome", the first among the seven deacons who served in the cathedral church. This was a position of great trust that included the care of the treasury and riches of the Church and the distribution of alms to the indigent.
St. Cyprian, Bishop of Carthage, noted that at the time the norm was that Christians who were denounced were executed and all their goods confiscated by the Imperial treasury. At the beginning of August 258, the Emperor Valerian issued an edict that all bishops, priests, and deacons should immediately be put to death. Pope Sixtus II was captured on August 6, 258, at the cemetery of St. Callixtus while celebrating the liturgy and was executed immediately.
After the death of Sixtus, the prefect of Rome demanded that Lawrence turn over the riches of the Church, and St. Ambrose wrote that Lawrence asked for three days to gather the wealth. He worked swiftly to distribute as much Church property to the indigent as possible to prevent it from being seized by the prefect. On the third day, at the head of a small delegation, he presented himself to the prefect. When ordered to deliver the treasures of the Church, he presented the city's indigent, crippled, blind, and suffering, and declared that these were the true treasures of the Church: "Here are the treasures of the church. You see, the church is truly rich, far richer than your emperor!"
Saint Lawrence was martyred on August 10, 258 along with many other members of the Roman clergy. He was the last of the seven deacons of Rome to die.